| Another generation
of kinase therapeutics will be
more broadly applicable, more
effective and with less patient
side-effects. |
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| Select Kinase inhibitors have been validated as effective therapies,
however: |
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Existing therapies will undergo significant improvement. |
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Nexavar,
a targeted therapy
recently approved
for renal cell carcinoma
and projected
to have peak sales
in excess of $500m,
extends average patient
survival by just three
months |
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Biological approaches such as Avastin require
bi-weekly hospital visits for transfusions. |
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All targeted therapeutics to date generate significant
side effects such as flu-like symptoms, nausea
and reduced energy. |
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| Xcovery's next generation drug discovery and development
efforts have shown to generate more specific, less
toxic , orally available small molecule leads with improved
performance in animal models. |
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